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Index > Protein center > Csnk2a1(Gene name) > Mouse
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  • Csnk2a1 (Gene name),
  • Casein kinase II subunit alpha (Protein name ),  CSK21_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Csnk2a1(Ckiia);
    Protein name:
    Casein kinase II subunit alpha(CK II alpha);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Tetramer composed of an alpha chain, an alpha' and two beta chains. Interacts with RNPS1. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
    Function:
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-389' of p53/TP53 following UV irradiation.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    391
    Sequence:
    50:
    MSGPVPSRAR | VYTDVNTHRP | REYWDYESHV | VEWGNQDDYQ | LVRKLGRGKY | 
    100:
    SEVFEAINIT | NNEKVVVKIL | KPVKKKKIKR | EIKILENLRG | GPNIITLADI | 
    150:
    VKDPVSRTPA | LVFEHVNNTD | FKQLYQTLTD | YDIRFYMYEI | LKALDYCHSM | 
    200:
    GIMHRDVKPH | NVMIDHEHRK | LRLIDWGLAE | FYHPGQEYNV | RVASRYFKGP | 
    250:
    ELLVDYQMYD | YSLDMWSLGC | MLASMIFRKE | PFFHGHDNYD | QLVRIAKVLG | 
    300:
    TEDLYDYIDK | YNIELDPRFN | DILGRHSRKR | WERFVHSENQ | HLVSPEALDF | 
    350:
    LDKLLRYDHQ | SRLTAREAME | HPYFYTVVKD | QARMSSTSMA | GGSTPVSSAN | 
    391:
    MMSGISSVPT | PSPLGPLAGS | PVIAAANSLG | IPVPAAAGAQ | Q
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CK II alpha
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    E10177h
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    ELISA Kit for Mouse CK II alpha
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    ELISA Kit for Mouse CK II alpha
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    ELISA Kit for Mouse CK II alpha
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    E10177m
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    96T
    ELISA Kit for Mouse CK II alpha
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    E10177r
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    MSDS:
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    Packing:
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    ELISA Kit for Mouse CK II alpha
    MSDS:
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    CLIA Kit for Mouse CK II alpha
    Cat.:
    U10177m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse CK II alpha
    Cat.:
    U10177r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CK II alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CK II alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CK II alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CK II alpha
    Cat.:
    U10177h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse CK II alpha
    Polyclonal Antibody for Mouse CK II alpha
    Polyclonal Antibody for Mouse CK II alpha
    Cat.:
    P10177Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CK II alpha
    Polyclonal Antibody for Mouse CK II alpha
    Polyclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Monoclonal Antibody for Mouse CK II alpha
    Protein for Mouse CK II alpha
    Protein for Mouse CK II alpha
    Protein for Mouse CK II alpha
    Protein for Mouse CK II alpha
    Protein for Mouse CK II alpha
    Protein for Mouse CK II alpha

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    References
    1. 1.
      "Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle."
      Seldin D.C. , Leder P.
      Science267:894-897(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: FVB/N.
      tissue: Spleen.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Inner ear.
      tissue: Liver.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      strain: FVB/N.
      tissue: Mammary tumor.
    6. 6.
      "Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells."
      Song D.H. , Sussman D.J. , Seldin D.C.
      J. Biol. Chem.275:23790-23797(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8."
      McDonnell M.A. , Abedin M.J. , Melendez M. , Platikanova T.N. , Ecklund J.R. , Ahmed K. , Kelekar A.
      J. Biol. Chem.283:20149-20158(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN APOPTOSIS
    8. 8.
      "The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development."
      Lou D.Y. , Dominguez I. , Toselli P. , Landesman-Bollag E. , O'Brien C. , Seldin D.C.
      Mol. Cell. Biol.28:131-139(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    9. 9.
      "Phosphorylation of serine 11 and serine 92 as new positive regulators of human Snail1 function: potential involvement of casein kinase-2 and the cAMP-activated kinase protein kinase A."
      MacPherson M.R. , Molina P. , Souchelnytskyi S. , Wernstedt C. , Martin-Perez J. , Portillo F. , Cano A.
      Mol. Biol. Cell21:244-253(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNAI1
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